Detecting pancreatic cancer earlier can lead to more patients being eligible for surgery and significantly higher survival rates. Evidence suggests that in a small subset of people with a new diabetes diagnosis after the age of 50, the diabetes is caused by a pancreatic tumor.

Whereas other large-scale pancreatic cancer early detection research efforts have focused on people at high risk due to family history or genetic changes, PanCAN and its partners are going to study the relationship between changes in blood sugar and weight and the development – and detection – of pancreatic cancer.

PanCAN’s Early Detection Initiative is a randomized trial to develop a feasible and cost-effective approach to detect pancreatic cancer when it can be surgically removed.

Working in collaboration with government and research institutions, the Early Detection Initiative will:

  • Evaluate if imaging at the time of new-onset diabetes results in detection of pancreatic cancer at an earlier stage of disease than it is typically diagnosed
  • Contribute blood samples to an established new-onset diabetes biobank maintained by the National Cancer Institute (NCI) for analysis of future pancreatic cancer biomarkers
  • Inform current clinical guidelines to develop a screening approach that will allow doctors to catch pancreatic cancer sooner in a subset of patients

WHO CAN PARTICIPATE IN PanCAN’S EARLY DETECTION INITIATIVE?

Patients will be selected through electronic health systems at participating healthcare institutions. Only people identified through their institution’s electronic health system will be able to participate in the study.

PanCAN’S EARLY DETECTION INITIATIVE STEERING COMMITTEE

PanCAN has brought together a multidisciplinary team of expert researchers, clinicians, statisticians and diagnostic specialists from around the country to design and conduct this study:

Suresh Chari, MD
Study Principal Investigator
University of Texas M.D. Anderson Cancer Center

Anirban Maitra, MBBS
Co-Principal Investigator
University of Texas M.D. Anderson Cancer Center

Bechien Wu, MD
Co-Principal Investigator
Kaiser Permanente Southern California

Avinash Kambadakone-Ramesh, MD, FRCR
Co-Principal Investigator
Massachusetts General Hospital, Harvard Medical School

Ziding Feng, PhD
Study Biostatistician
Fred Hutchinson Cancer Research Center

Elisabeth Beaber, PhD
Co-Investigator/Epidemiologist
Fred Hutchinson Cancer Research Center

Sudhir Srivastava, PhD, MPH
National Cancer Institute, Division of Cancer Prevention, Cancer Biomarkers Research Group

Jo Ann Rinaudo, PhD
National Cancer Institute, Division of Cancer Prevention, Cancer Biomarkers Research Group

Barbara Kenner, PhD
Kenner Family Research Fund

INTERESTED IN SUPPORTING PanCAN’S EARLY DETECTION INITIATIVE?

Every dollar you give makes programs like the Early Detection Initiative possible.
If you’re interested in making a gift to support this initiative, please contact Allyssa Miranda at amiranda@pancan.org or (310) 706-3343.
We can’t do this without donors like you.

ANY QUESTIONS?

Contact PanCAN’s Patient Services to learn more about our Early Detection Initiative and for personalized information and resources about the diagnosis and treatment of pancreatic cancer.