Patients treated with matched therapies selected through molecular profiling have better outcomes1. The Pancreatic Cancer Action Network (PanCAN) supports the guidelines’ recommendations to obtain tumor tissue suitable for molecular profiling. PanCAN offers information and resources related to precision medicine, including the Know Your Tumor precision medicine service, for you and your patients.

1PanCAN's Public Statements for Healthcare Professionals, including references.

Valuable Information to Support Your Treatment Decisions

PanCAN’s Know Your Tumor precision medicine service is provided in partnership with Tempus, a CLIA-certified laboratory. The service provides you with a molecular profiling report of your patient’s tumor and treatment options, providing valuable insight to support your treatment decisions.

More than 400 physicians – from institutions such as Cedars-Sinai Medical Center, Johns Hopkins, Virginia Mason Medical Center and Memorial Sloan-Kettering – have received Know Your Tumor reports for their patients. About 27 percent of patients’ tumors have been found to have at least one actionable alteration.

Contact PanCAN’s Healthcare Professional Services for more information.

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“Know Your Tumor is a very important effort to improve the care provided to pancreatic cancer patients. We gain an important understanding of tumor biology, which leads to more precise selection of treatments. This is personalized medicine at its best.”

— Dr. Andrew E. Hendifar
Medical oncology lead for the gastrointestinal disease research group at Cedars-Sinai Medical Center

More Treatment Options

The Know Your Tumor report includes treatment options, providing valuable insight to support your treatment decisions.

Treatment options, personalized to your patient, may include:

  • Targeted therapy, which avoids the toxicity of multi-agent chemotherapy

  • Appropriate clinical trials, including molecularly targeted solid tumor trials

  • Off-label treatments that may be particularly effective for your patient’s specific tumor mutations

  • Standard of care treatments

Our Trusted Partners

PanCAN partners with Tempus, a CLIA-certified laboratory that uses the xT gene panel for testing. The report includes information on both somatic and germline mutations, tumor burden (TMB) and microsatellite instability (MSI).

PanCAN partners with Perthera, Inc., to publish research supported by data from the Know Your Tumor program. These efforts will help improve patient outcomes by providing important research findings to the healthcare professional community.

The Know Your Tumor Process


The following criteria will help you decide which patients are best suited for Know Your Tumor:

  • Patient has diagnosis of pancreatic malignancy

  • Tumor tissue is obtainable (see TEMPUS Specimen Guidelines)

  • Patient has no sign of progression or impending need to change treatment

    • Completion and delivery of the report takes approximately 14 days from receipt of tissue

  • Patient is receiving treatment for a pancreatic cancer diagnosis in the United States or Canada and is not imprisoned

  • Patient or close caregiver reads and speaks English or Spanish

Know Your Tumor Resources

We're Here to Help

Our Healthcare Professional Services has dedicated staff to provide one-to-one support for healthcare professionals.