The Pancreatic Cancer Action Network Translational Research Grants support independent investigators conducting translational research that has as its endpoint the development of a pancreatic cancer assessment, prevention or treatment modality. The grant provides $300,000-$500,000 over two years.
The Translational Research Grant was established in 2014, and to date, 23 grants have been awarded.
2016 Pancreatic Cancer Action Network Translational Research Grant
Pratip Bhattacharya, PhD
Co-PI: Florencia McAllister, MD
MD Anderson Cancer Center
Early Detection of PanIN by Hyperpolarized Metabolic MR Imaging
2017 Gail V. Coleman-Kenneth M. Bruntel – Pancreatic Cancer Action Network Translational Research Grant
Vladimir Bogdanov, PhD
Co-PI: Syed Arif Ahmad, MD
University of Cincinnati
Disrupting Tissue Factor-beta1 Integrin Axis in Pancreatic Cancer
2015 Pancreatic Cancer Action Network Translational Research Grant
David Boothman, PhD, UT Southwestern Medical Center
Co-PI: Muhammad Beg, MD
Use of PARP1 inhibitors to leverage a tumor-selective ‘kiss of death’
2016 Pancreatic Cancer Action Network Translational Research Grant
Erica Carpenter, MBA, PhD
Co-PI: Ben Stanger, MD, PhD
University of Pennsylvania
Real-time Monitoring of Exosomes as a Biomarker for Pancreatic Cancer
2018 Pancreatic Cancer Action Network Translational Research Grant
Darren Carpizo, MD, PhD, Rutgers, The State University of New Jersey
Co-PI: Patrick Mehlen, PhD, Université Claude Bernard Lyon 1
Investigating Netrin-1 as a New Therapeutic Target in Pancreatic Cancer
2018 Pancreatic Cancer Action Network Translational Research Grant
Michael Curran, PhD
MD Anderson Cancer Center
Pro-Inflammatory Conversion of the PDAC Microenvironment
2017 Pancreatic Cancer Action Network Translational Research Grant
Giulio Draetta, MD, PhD
MD Anderson Cancer Center
Therapeutic Vulnerabilities of Mesenchymal Pancreatic Cancer Cells
2018 Pancreatic Cancer Action Network Translational Research Grant
Sharon Gorski, PhD, British Columbia Cancer Agency Branch (BC Cancer)
Co-PI: Robert Young, PhD, MC, FRSC, Simon Fraser University
ATG4 Family Members as Therapeutic Targets for Pancreatic Cancer
2016 Pancreatic Cancer Action Network Translational Research Grant
Claudia Gravekamp, PhD, Albert Einstein College of Medicine
Co-PI: Jennifer Chuy, MD, Montefiore Medical Center
Improving Cancer Immunotherapy and Gemcitabine Sensitivity through Listeria
2016 Abby Sobrato – Pancreatic Cancer Action Network Translational Research Grant
Philip Greenberg, MD
Fred Hutchinson Cancer Research Center
Targeting PDA with T-Cells Engineered to Express a Mesothelin-Specific TCR
2016 Pancreatic Cancer Action Network Translational Research Grant
William Hawkins, MD
Washington University in St. Louis
Targeting Tumor Infiltrating Myeloid Cells to Enhance Immunotherapy
2017 Pancreatic Cancer Action Network Translational Research Grant
Steven Hughes, MD
University of Florida
Protein Signatures Improve the Diagnostic Yield of Fine Needle Aspiration
2016 Pancreatic Cancer Action Network Translational Research Grant
David Iannitti, MD, Carolinas Medical Center
Co-PI: Rafael Davalos, PhD, Virginia Polytechnic Institute and State University
Developing Next Generation IRE to Treat Pancreatic Cancer
2016 Pancreatic Cancer Action Network Translational Research Grant
Ann Leen, PhD
Co-PI: William Fisher, MD
Baylor College of Medicine
T-Cell Therapy for Pancreatic Cancer
2015 Pancreatic Cancer Action Network Translational Research Grant
David Linehan, MD
University of Rochester
Targeting Inflammatory Monocytes in Metastatic Pancreas Cancer
2018 Pancreatic Cancer Action Network Translational Research Grant
Scott Lowe, PhD
Sloan-Kettering Institute for Cancer Research
Targeting p53 Mutations in Pancreatic Ductal Adenocarcinoma
2015 Pancreatic Cancer Action Network Translational Research Grant
Nipun Merchant, MD, University of Miami
Co-PI: Michael VanSaun, PhD
Targeting downstream effectors of KRAS via MEK and CDK-4 inhibition in PDAC
2018 Pancreatic Cancer Action Network Translational Research Grant
George Miller, MD
Co-PI: Shohei Koide, PhD
Perlmutter Cancer Center at NYU Langone
Central Role of TIM4 in Driving Immune Tolerance in Pancreatic Carcinoma
2018 Pancreatic Cancer Action Network Translational Research Grant
Kenneth Shroyer, MD, PhD
Stony Brook University
Keratin 17 Is a Novel Actionable Target in Pancreatic Ductal Adenocarcinoma
2016 Pancreatic Cancer Action Network Translational Research Grant
Aatur Singhi, MD, PhD
University of Pittsburgh
Diagnostic Markers of Malignant Transformation in Mucinous Pancreatic Cysts
2015 Pancreatic Cancer Action Network Translational Research Grant
Kazuki Sugahara, MD, PhD, Columbia University
Co-PI: Andrew Lowy, MD, FACS, University of California, San Diego
Clinical development of a tumor-penetrating peptide for enhanced pancreatic cancer therapy
2014 Pancreatic Cancer Action Network – Translational Continuation Research Grant
David Ting, MD
Massachusetts General Hospital
Circulating Tumor Cells to Assess Pancreatic Cancer Disease Status
2017 Tap Cancer Out – Pancreatic Cancer Action Network Translational Research Grant
Timothy C. Wang, MD
Co-PI: Paul Oberstein, MD
Columbia University
Targeting Cholinergic Receptors to Suppress Pancreatic Cancer
