Etiology

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New studies focused on genetic, environmental or lifestyle factors that influence risk.

 

Ambry to Present New Data Showing That up to 30% of Cancer Risk Carriers Are Missed by Current Testing Guidelines at the 2017 ASCO Meeting
ASCO abstract

  • Meeting: 2017 American Society of Clinical Oncology (ASCO) Annual Meeting
  • Institution(s): Beth Israel Deaconess Medical Center, Cambridge, MA, and others
  • Lead author(s): Mary Linton Bounetheau Peters
  • Major finding: Preliminary results show that 6.6% of unselected pancreatic ductal adenocarcinoma (PDAC) patients carry a germline mutation in a gene known to increase PDAC risk and 4.3% have a mutation in genes not previously linked to PDAC. Existing testing criteria did not identify 30% of carriers. Continued refinement of guidelines is necessary to align genetic testing with inherited PDAC risk.

 
 

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