Celiac Plexus Block

Home Facing Pancreatic Cancer Living with Pancreatic Cancer Managing Side Effects Pain Management Celiac Plexus Block

On This Page:

What Is the Celiac Plexus?

The celiac plexus is a nerve bundle in the upper abdomen. It is located behind the pancreas and near the aorta.

The celiac nerves connect the pancreas, gall bladder, intestines, liver and stomach to the brain and spinal cord. Pancreatic tumors often cause pain by pressing on and injuring these nerves.

What Is a Celiac Plexus Block?

A celiac plexus block is a procedure that damages the celiac nerves so they cannot send pain messages to the brain. It is sometimes used to treat abdominal pain in pancreatic cancer patients.

Why Use a Celiac Plexus Block?

Patients with advanced pancreatic cancer often have intense abdominal pain. They often use strong pain medicines, such as opioids, to control this pain.

Even patients who use pain medicines may still have breakthrough pain, or periods of intense pain. Additionally, pain medicines can also cause uncomfortable side effects, like constipation.

A celiac plexus block can help a patient avoid breakthrough pain. The block usually does not stop all the pain. But it may lessen the need to use pain medicines.

What Happens During the Procedure?

A celiac plexus block can happen three ways:

In all cases, a doctor injects a painkiller to numb the celiac nerves. Then they inject a substance to damage the nerves.

For more information about each of these approaches, contact Patient Central.

How Long Does It Take?

The celiac plexus block procedure takes 30-60 minutes. The total procedure time depends on how the doctor accesses the celiac nerves.

What Happens After the Procedure?

Most patients feel some, although not total, relief from pain after the procedure. Since the nerve block typically lasts three to six months, patients may need to repeat the procedure.

What Are Possible Side Effects?

Complications related to a celiac plexus block can be serious. The procedure is not recommended for patients taking blood-thinning medicines or who have an infection or bowel blockage.

Common side effects include:

  • Low blood pressure (hypotension)
  • Diarrhea
  • Pain, tenderness, swelling or bruising around the injection
  • Muscle spasm at the area of injection

Though less common, the following are also possible side effects:

  • Delayed gastric emptying
  • Damage to kidneys
  • Paralysis
  • Seizure or lowered blood supply to the spinal cord
  • Allergic reaction to the dye or medicines injected
  • Accidental puncture of an organ
  • Infection (increased redness or swelling) at the injection or IV site

Talk with your healthcare team about the benefits and risks to decide if a celiac plexus block is the right choice to control your pain.

Managing Side Effects

A celiac plexus block is one way to control the pancreatic cancer symptom of abdominal pain.

Seeing healthcare professionals who focus on symptom management and supportive (palliative) care improves outcomes and is critical for your quality of life. The Pancreatic Cancer Action Network strongly recommends that symptom management and supportive (palliative) care should be provided early in your diagnosis as well as during and after treatment.

We’re Here to Help

For free, in-depth and personalized  information about symptom and side effect management, including celiac plexus blocks, contact Patient Central.

Related Topics

  • Pain

    Learn more about pancreatic cancer pain and how to control it.

  • Supportive Care

    See how supportive care can lessen disease side effects and symptoms.


Information reviewed by PanCAN’s Scientific and Medical Advisory Board, who are experts in the field from such institutions as University of Pennsylvania, Memorial Sloan-Kettering Cancer Center, Virginia Mason Medical Center and more.

Information provided by the Pancreatic Cancer Action Network, Inc. (“PanCAN”) is not a substitute for medical advice, diagnosis, treatment or other health care services. PanCAN may provide information to you about physicians, products, services, clinical trials or treatments related to pancreatic cancer, but PanCAN does not recommend nor endorse any particular health care resource. In addition, please note that any personal information you provide to PanCAN’s associates during telephone and/or email communications may be stored and used to help PanCAN achieve its mission of assisting patients with, and finding cures and treatments for, pancreatic cancer. Stored constituent information may be used to inform PanCAN programs and activities. Information also may be provided in aggregate or limited formats to third parties to guide future pancreatic cancer research and treatment efforts. PanCAN will not provide personal directly identifying information (such as your name or contact information) to such third parties without your prior written consent unless required or permitted by law to do so.

Wage Hope With Us

Join us to double pancreatic cancer survival by 2020.





shop purple logo

Gear, apparel, accessories and more to show off your purple pride.


Shop Now 

©2018 Pancreatic Cancer Action Network. All rights reserved. Terms of Use | Privacy Policy


Pancreatic Cancer Action Network®, PanCAN®, PurpleStride®, Wage Hope®, Know Your Tumor®, Powerful Knowledge. Personal Treatment.®, Precision Promise℠ and Demand Better For Patients. For Survival.℠ are the trademarks of the Pancreatic Cancer Action Network, Inc.


The Pancreatic Cancer Action Network is registered as a 501©3 nonprofit organization. Contributions to the Pancreatic Cancer Action Network are tax-deductible to the extent permitted by law. The Pancreatic Cancer Action Network’s tax identification number is #33-0841281.