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Types of Exocrine Pancreatic Cancer

Exocrine tumors account for 95% of all pancreatic cancers.  There are still many types of exocrine tumors, including the most common type: adenocarcinoma.

Type
Description

Acinar Cell Carcinoma

This rare cancerous tumor may cause excessive production of pancreatic digestive enzymes.
Adenocarcinoma This type of tumor accounts for 75% of all pancreas cancers and arises from cells lining the pancreatic duct.  Adenocarcinomas may form glands, or a collection of cells surrounding an empty space.
Adenosquamous Carcinoma This type of tumor is similar to adenocarcinoma in that it forms glands, but it flattens as it grows.  It can mimic other types of cancer that show squamous differentiation.
Giant Cell Tumor This type of tumor is extremely rare and is not as aggressive as adenocarcinoma.  It has unusually large cells, but the tumor is not any larger than other pancreatic tumors.
Intraductal Papillary-Mucinous Neoplasm (IPMN) This tumor grows from the pancreatic duct or off side branches of the duct.  The tumor appears to be a fingerlike projection into the duct.  It can be diagnosed as benign or malignant.
Mucinous  Cystadenocarcinoma This rare, cystic, fluid-containing tumor can develop into cancer over time.  The space within the spongy tumor is filled with a think fluid called mucin.  This type of tumor has a better prognosis than other pancreatic tumors.
Pancreatoblastoma This rare, malignant tumor is found primarily in children under that age of 10.  It is often called pancreatic cancer of infancy.  The prognosis is better than other forms of pancreatic cancer.
Serous Cystadenocarcinoma This is a rare, benign, cystic, fluid-containing tumor with a sponge-like appearance.  It can grow to be quite large and is almost always benign.
Solid and Pseudopapillary Tumors These tumors can arise anywhere in the pancreas.  Some parts of the tumor are solid, while other parts are papillary (finger-like projections).  It is primarily found in women in their 30's.

 

Metastatic Pancreatic Cancer

When pancreatic cancer spreads (metastasizes) outside the pancreas, it is often found in nearby lymph nodes.  Lymph nodes are part of the extensive lymph system of vessels and ducts throughout the entire body that help filter and remove foreign materials.  If there are cancer cells in the lymph nodes, it is possible that the cancer has also spread to other distant organs or tissues, such as the liver or lungs.  Sometimes, pancreatic cancer cells spread to the tissue that lines the abdomen, the peritoneum.  Because these cancer cells in these other locations originated in the pancreas, they are still con sidered pancreatic cancer cells and will be treated as such.

Links to additional resources:


National Cancer Institute

MedLine Plus - A Service of the National Library of Medicine

MD Anderson Cancer Center

Johns Hopkins University

Greenebaum Cancer Center Pancreatic Cancer Overview

Presbyterian Hospital of Dallas - Digestive System Information


The Pancreatic Duct

Cancer Consultants - Pancreatic Cancer Information Center


CancerAnswers.com


Cancer Links USA



 

 

  The information and services provided by the Pancreatic Cancer Action Network, Inc. (PanCAN) are for informational purposes only. The information and services are not intended to be substitutes for professional medical advice, diagnosis or treatment. If you are ill, or suspect that you are ill, see a doctor immediately! PanCAN does not recommend or endorse any specific physicians, products or treatments even though they may be mentioned on this site.
 
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